Researchers at the Indian Institute of Technology Mandi have used natural polymer based smart nanoparticles to treat colorectal cancer. These nanoparticles release the drug in response to stimuli that are specific to cancer site only.
Researchers at the Indian Institute of Technology Mandi in collaboration with the University of Cincinnati, USA, has developed an efficient method to study the internal structure and functions of an important compone
The findings offer new diagnostic and therapeutic tools for fatty-liver induced diabetes
Researchers at the Indian Institute of Technology (IIT) Mandi and Durham University in the United Kingdom, have developed suction monitoring setup for soil cyclic triaxial testing to investigate the impact of climate change on railway embankments. The study was conducted by Dr Ashutosh Kumar, Assistant Professor, School of Engineering, IIT Mandi, and co-authored by Dr Arash Azizi, Assistant Professor, University of Portsmouth, UK and Professor David Geoffrey Toll, Department of Engineering, Durham University, UK, IIT Mandi said in an official statement.
IIT Mandi researchers elucidate the molecular structure of Endodomain of the spike protein of the COVID-19 virus
Using advanced computational algorithms and laboratory techniques, the researchers have deciphered the structural
flexibilities of the C-terminal region
India has experienced a very high infection rate of COVID-19, leading to a collapse of health infrastructure. According to the study, a robust emergency plan to mitigate the spread of the next pandemic needs to be carefully planned. Knowledge of regions on the trajectory of a pandemic, reported here, will help better manage a future outbreak. This analysis will be useful for policymaking
A research team from the Indian Institute of Technology Mandi led by Dr. Rajanish Giri, Associate Professor, School of Basic Sciences, IIT Mandi, have discovered an important biomolecular mechanism for the formation of protein clusters/aggregates that are often seen in Alzheimer’s disease. They have shown that signal peptide of the Amyloid Precursor Protein (APP) can co-aggregate with Amyloid beta peptide (Aβ42). This Aβ42, known for the pathogenesis of Alzheimer’s disease, a most common form of dementia that slowly destroys memory and other important mental functions.
Indian Institute of Technology Mandi researchers have used hydrochar derived from orange peels as catalyst to convert biomass derived chemicals into biofuel precursors. The research will help to develop biomass-based fuel to overcome the socio-political instabilities associated with dwindling petroleum reserves.